alt text: A "xit" from user @ChrpngBrd in which he responds to another "xit" from @BlueBoxDave that says "If Israel falls then America falls. It's that simple." @ChrpngBrd's response is a thumbs up emoji, and two stills from The Simpsons S02E19 "Lisa's Substitute." In which, the first image is Martin Prince putting up a poster saying "A vote for Bart is a vote for Anarchy!" and the second image is Bart Simpson putting up a poster that says "A vote for Bart is a vote for Anarchy!"
Israel isn't easily replaceable in US foreign policy for the Middle East. I.e. the US uses Israel as a base of operations in the area. But the US definitely doesn't need Israel for it's survival or even to exert influence on the Middle East: it just makes it easier.
The US didn’t have a base in Israel till 2017, it’s never really been a significant base of operation for US forces. Us forces have more presence in basically every country in the region with the exception of Yemen, Egypt and Iran. Hell, there’s even a base Syria.
And there's a nato member a little bit north of Israel.
I think we're good.
https://www.reuters.com/graphics/ISRAEL-PALESTINIANS/USA-MILITARY-BASES/zdvxnnynmvx/chart.png
With declining importance of oil, the US has less reason to give a shit about the Middle East. We're a ways off from that point, but it's coming.
If you think the Middle East is fucked up now, just wait until there's a power vacuum from nobody caring about oil anymore.