Science

A 25-year-old woman with type 1 diabetes started producing her own insulin less than three months after receiving a transplant of reprogrammed stem cells1. She is the first person with the disease to be treated using cells that were extracted from her own body.

“I can eat sugar now,” said the woman, who lives in Tianjing, on a call with Nature. It has been more than a year since the transplant, and, she says, “I enjoy eating everything — especially hotpot.” The woman asked to remain anonymous to protect her privacy.

James Shapiro, a transplant surgeon and researcher at the University of Alberta in Edmonton, Canada, says the results of the surgery are stunning. “They’ve completely reversed diabetes in the patient, who was requiring substantial amounts of insulin beforehand.”

Here is the report: We Can’t Write the Truth Anymore’: Academic Freedom in Hong Kong Under the National Security Law (pdf)

• Academic freedom in Hong Kong has severely declined since the Chinese government imposed the draconian National Security Law on the city on June 30, 2020.
• Students and faculty accustomed to academic freedom must now tread carefully to avoid retribution for what they teach, research, and publish, and even with whom they associate.
• Concerned governments and foreign universities with partnerships with Hong Kong universities should speak up for affiliated academics and students, and review these partnerships to avoid becoming complicit in human rights violations.

Academic freedom in Hong Kong has severely declined since the Chinese government imposed the draconian National Security Law on the city on June 30, 2020, Human Rights Watch and Hong Kong Democracy Council said in a report released today.

The 80-page report, “‘We Can’t Write the Truth Anymore’: Academic Freedom in Hong Kong Under the National Security Law,” documents that long-protected civil liberties, including the rights to freedom of expression, assembly, and association, have been under assault in Hong Kong’s eight publicly funded universities. As these universities have become increasingly repressive, students and faculty widely self-censor, fearful of being targeted for harassment, retribution, and even prosecution for what they say and do both in the classroom and on campus.

Abstract (added emphasis and paragraphing):

Anthropogenic methane (CH4) emissions increases from the period 1850–1900 until 2019 are responsible for around 65% as much warming as carbon dioxide (CO2) has caused to date, and large reductions in methane emissions are required to limit global warming to 1.5°C or 2°C.

However, methane emissions have been increasing rapidly since ~2006. This study shows that emissions are expected to continue to increase over the remainder of the 2020s if no greater action is taken and that increases in atmospheric methane are thus far outpacing projected growth rates.

This increase has important implications for reaching net zero CO2 targets: every 50 Mt CH4 of the sustained large cuts envisioned under low-warming scenarios that are not realized would eliminate about 150 Gt of the remaining CO2 budget. Targeted methane reductions are therefore a critical component alongside decarbonization to minimize global warming.

We describe additional linkages between methane mitigation options and CO2, especially via land use, as well as their respective climate impacts and associated metrics. We explain why a net zero target specifically for methane is neither necessary nor plausible. Analyses show where reductions are most feasible at the national and sectoral levels given limited resources, for example, to meet the Global Methane Pledge target, but they also reveal large uncertainties.

Despite these uncertainties, many mitigation costs are clearly low relative to real-world financial instruments and very low compared with methane damage estimates, but legally binding regulations and methane pricing are needed to meet climate goals.

https://www.lieffcabraser.com/antitrust/academic-journals/

https://www.forbes.com/sites/michaeltnietzel/2024/09/16/scientists-file-antitrust-lawsuit-against-six-journal-publishers/

https://www.reuters.com/legal/litigation/academic-publishers-face-class-action-over-peer-review-pay-other-restrictions-2024-09-13/

"On September 12, 2024, Lieff Cabraser and co-counsel at Justice Catalyst Law filed a federal antitrust lawsuit against six commercial publishers of academic journals, including Elsevier, Springer Nature, Taylor and Francis, Sage, Wiley, and Wolters Kluwer, on behalf of a proposed class of scientists and scholars who provided manuscripts or peer review, alleging that these publishers conspired to unlawfully appropriate billions of dollars that would otherwise have funded scientific research."

"Deutsche Bank aptly describes the Scheme as a “bizarre” “triple pay system” whereby “the state funds most of the research, pays the salaries of most of those checking the quality of the research, and then buys most of the published product.”"

Abstract

Rapa Nui (also known as Easter Island) is one of the most isolated inhabited places in the world. It has captured the imagination of many owing to its archaeological record, which includes iconic megalithic statues called moai1. Two prominent contentions have arisen from the extensive study of Rapa Nui. First, the history of the Rapanui has been presented as a warning tale of resource overexploitation that would have culminated in a major population collapse—the ‘ecocide’ theory2,3,4. Second, the possibility of trans-Pacific voyages to the Americas pre-dating European contact is still debated5,6,7. Here, to address these questions, we reconstructed the genomic history of the Rapanui on the basis of 15 ancient Rapanui individuals that we radiocarbon dated (1670–1950 ce) and whole-genome sequenced (0.4–25.6×). We find that these individuals are Polynesian in origin and most closely related to present-day Rapanui, a finding that will contribute to repatriation efforts. Through effective population size reconstructions and extensive population genetics simulations, we reject a scenario involving a severe population bottleneck during the 1600s, as proposed by the ecocide theory. Furthermore, the ancient and present-day Rapanui carry similar proportions of Native American admixture (about 10%). Using a Bayesian approach integrating genetic and radiocarbon dates, we estimate that this admixture event occurred about 1250–1430 ce.

Fascinating, I like this kind of Magick.

I believe the problem is never showing evidence, but that the evidence is overwhelming. I could explain the general idea and, maybe, one or two specifics. People that use the XX/XY binary argument wouldn’t be able to explain either, but it’s usually only used because it conforms to a bias. And we are only talking about humans here. Language would implode if we tried to maintain convenient binaries and still back it up with science.

A US military veteran who received the world's first whole-eye transplant has made significant progress a year later and has been able to resume his normal life, researchers say.

Aaron James, 46, also received a rare partial-face transplant. He lost most of his face in an accident in 2021 while working as a high-voltage utility lineman.

His donor eye has so far maintained normal pressure and blood flow and retained its size, unlike donor eyes in animals that often shrink after transplants, researchers at NYU Langone Health said in a new study.

Mr James has not regained sight in that eye, but researchers are hopeful he might eventually be able to see out of it again.

[...]

Last May, he underwent 21 hours of surgery that involved more than 140 healthcare professionals.

The donated face and eye came from a single male donor in his 30s. During the surgery, doctors injected adult stem cells from the donor's bone marrow into the optic nerve to encourage its repair.

[...]

The 46-year-old military veteran is only the 19th person in the US to undergo a face transplant and the first person in the world to receive an entire human eye transplant.

China’s influence increasingly threatens the academic world in Brazil. In recent years, the country’s main higher education institutions, such as the State University of Campinas (Unicamp) and the Federal University of Minas Gerais (UFMG), have established partnerships with Chinese institutions at an ever-increasing rate. Experts warn of the risks of this growing soft power that Beijing uses to promote the Chinese model.

“China’s influence on Brazilian universities has never been greater,” journalist Gabriel de Arruda Castro, editor of Brazilian daily Gazeta do Povo, told Diálogo. “Obviously, this opens the door to the presence of representatives of an authoritarian regime, which is not the case when Brazil establishes academic partnerships with countries like Germany or France.”

[...]

Although agreements between Brazilian and foreign universities are common, Castro points out that these countries respect the independence and academic autonomy of their teaching centers. Chinese universities, on the other hand, are subject to the strict control of the Beijing government. “From the point of view of the Chinese regime, it doesn’t make any sense to fund any project that might be critical of the Chinese model,” says Castro.

[...]

Part of the Chinese influence in Brazilian universities is exerted through partnerships with the Confucius Institute, an entity linked to the Chinese Ministry of Education, whose official mission is to spread Chinese culture and language.

[...]

On August 13, 2020, the U.S. State Department designated the Confucius Institute as a “foreign mission” of China, noting that it promotes “Beijing’s global propaganda and malign influence campaign” in classrooms.

[...]

In 2023, Germany’s Federal Office for the Protection of the Constitution (BfV) called the Confucius Institute a tool of political influence. “China’s activities and forms of cooperation threaten to undermine academic freedom in the field of education and research,” the BfV said in its annual report, German news agency Deutsche Welle reported.

[...]

“Obviously, the official view of the regime is not challenged in these cases. The promotion of Chinese culture is therefore mixed with the promotion of the Chinese regime,” says Castro. “In my research, I didn’t find any perspective critical of China.”

[...]

He believes there may be a risk of espionage by China in these initiatives. “Perhaps because it is not perceived as a direct adversary of China, Brazil has a little less of this aspect [of espionage]. But perhaps there is ‘soft espionage’ here: knowing where Brazil stands in certain areas of knowledge, in order to later use this as a strategic advantage in a possible competition in some area or to offer solutions,” he says.

“This is more or less what it [China] does in Africa by other means. In other words: meeting local demand pragmatically at first, but making these countries increasingly dependent on China,” Castro added.

[...]

Edit: The paper is total nonsense. Sorry for wasting people's time.

https://youtu.be/Yk_NjIPaZk4?si=dasxM2Py-s654djW

Here is the study: http://www.science.org/doi/10.1126/science.adg0344

A deadly pandemic has decimated bats in North America — and that has ultimately had harmful effects on humans, including higher rates of infant mortality, according to a new study.

The research is part of growing evidence that humans rely on the animal and plant species around them, and are harmed when those species decline or go extinct.

White-nose syndrome is a deadly fungal disease that kills an average of 70 per cent of bats it infects, and has been spreading to new areas since it was first reported on the continent in 2006.

[...]

Ecologists know that bats play a crucial role in eating up and controlling insect pests.

Because of that, Eyal Frank, an environmental economist at the University of Chicago, decided to look at what happened when white-nose syndrome spread into new counties in the eastern U.S., decimating bat populations.

He found that farmers responded to the resulting insect outbreaks by increasing their pesticide use 31 per cent. Pesticides are toxic, and often associated with human health impacts such as increases in infant deaths.

Frank found that infant mortality went up eight per cent after the arrival of white-nose syndrome in a county, according to his study published today in the journal Science.

[...]

The study shows how interactions between species such as bats and insects stabilize the ecosystems that other species rely on, including humans, who can be harmed when those species disappear, Frank said.

"These ecosystems are very complex systems with many interactions between species, and we do not fully understand what to expect or what will happen when we allow one species to fall below some viable population level or to go extinct," said Frank, who had previously linked the deaths of half a million people in India to the collapse of local vulture populations due to accidental poisoning.

Archived version

You probably haven’t heard of cardiologist Don Poldermans, but experts who study scientific misconduct believe that thousands of people may be dead because of him.

Poldermans was a prolific medical researcher at Erasmus Medical Center in the Netherlands, where he analyzed the standards of care for cardiac events after surgery, publishing a series of definitive studies from 1999 until the early 2010s.

One crucial question he studied: Should you give patients a beta blocker, which lowers blood pressure, before certain surgeries? Poldermans’s research said yes. European medical guidelines (and to a lesser extent US guidelines) recommended it accordingly.

The problem? Poldermans’s data was reportedly fake. A 2012 inquiry by Erasmus Medical School, his employer, into allegations of misconduct found that he “used patient data without written permission, used fictitious data and… submitted to conferences [reports] which included knowingly unreliable data.” Poldermans admitted the allegations and apologized, while stressing that the use of fictitious data was accidental.