No problems, just follow the cable suggestion from "badgerAteMyHomework".
Start at the top attach a small weight to the cable, https://www.amazon.com/Monoprice-Cat6-Ethernet-Patch-Cable/dp/B01M3VDWKB and let gravity do the work of running it downstairs.
Power line is no replacement for a decent wired or even 6GHz backhaul