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Alright, now THAT would be a perception thing, in that I fully believe that you default to the Oxford comma and fill in an alleged difference between those two reads of the sentence in your head where I do not. I don't believe it's a regional thing at all. You can overinflect through the ambiguity, but you're way more likely to simply construct the sentence unambiguously.

And no, it's not as hard as you make it out to be. There are so many little ways you'd adjust that line in speech without even thinking about it. Like I said, you can say "I invited the strippers and also Stalin and JFL" or "I invited the strippers, that's Stalin and JFK", neither of which are ambiguous no matter how you pronounce them. You could go "I invited the strippers, you know, Stalin and JFK", or say "I invited the strippers, I invited Stalin and JFK,...".

All of those are way more likely to subconsciously be used as a workaround to the ambiguity that absolutely is there in speech rather than have the listener go 'sorry, was that a long pause or a short pause before the "and"?'

But yeah, we do agree that with no consensus about the Oxford comma, the existence of the Oxford comma makes these sentences MORE ambiguous, not less, even if you consistently use the Oxford comma. Whether you think it's a better solution or not, with no universal authority on the subject the solution to the problem is to correctly phrase the sentence for clarity if needed. But many of the examples provided for this are deliberately obtuse and do not need any adjustment, being obvious in context.