Longtime Debian and Arch veteran here. I moved most of my workstations to Silverblue earlier this year (maybe 8 months ago now), and I've been very happy overall.
There is a bit of a learning curve if you aren't familiar with Flatpak or container-based workflows, assuming you wish to embrace those elements, but the curve is nowhere near as steep or unconventional as NixOS.
I love the automated updates. The flexibility to rebase or rollback the core OS on the fly, without any extra work, is great too. For example, it's very easy to test out beta releases, remixes, and preconfigured software bundles like uBlue.
I still use Arch for 99% of my command line tasks, inside a container managed by distrobox.
I strongly believe that Flatpak is the future of Linux software deployment, and although the format still has its kinks, it is already quite mature and will only get better as more and more upstream developers adopts its use.